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Week 7 College Football Picks, Predictions, Odds

Week 6 in NCAA football brought many surprises, upsets, and bone-crunching action. Week 7 will undoubtedly follow up with some more, so get ready by grabbing these college football picks, predictions and odds.

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Week 7 College Football Picks, Predictions, Odds and Previews

No. 2 Clemson (6-0) at Syracuse (3-3), 7 p.m. ET Friday

Spread: Clemson -22.5
Over/Under: 56

Last year, Clemson steamrolled over Syracuse 54-0. Outplaying Syracuse is something the Tigers are accustomed to and this game won’t be different. However, Clemson’s Kelly Bryant will play with ailing ankle which might limit his mobility. The spread favors Clemson by 22.5 points; even with Bryant’s ankle the Tigers will cover.

Pick: Clemson -22.5

No. 8 Washington State (6-0) at California (3-3), 10:30 p.m. ET Friday

Spread: Washington State: -15
Over/Under: 54.5

The Cougars’ passing attack is as deadly as ever, racking up yards and touchdowns galore. They’ve also taken strides to defend against the pass, which favors Washington State in this game. Expect a high scoring affair from the Cougars.

Pick: OVER 54.5

No. 20 North Carolina State (5-1) at Pittsburgh (2-4), noon ET

Spread: North Carolina State -11
Over/Under: 54

North Carolina’s Week 1 loss to South Carolina is their only blemish this year. Even so, the Pack then won over Florida State and Louisville which got them in the polls. Meanwhile, Pittsburgh hasn’t moved the needle this year and, in fact, bleeds yards in game after game. While it won’t be a blowout, expect at least 40 points from the Wolfpack.

Pick: OVER 54

No. 6 TCU (5-0) at Kansas State (3-2), noon ET

Spread: TCU -6.5
Over/Under: 51

This will be TCU’s first real challenge against a dual-threat Jesse Ertz or Alex Delton. The Horned Frogs will also be on the road which further complicates things. Kansas State will fight tooth and claw to defend its turf, but they’ll need a better effort than what they made against Texas lest to avoid a blowout.

Pick: Kansas State +6.5

No. 24 Texas Tech (4-1) at West Virginia (3-2), noon ET

Spread: West Virginia -3.5
Over/Under: 51

Expect this to be a high-scoring affair of at least 80 points or more. Both of these teams rank outside the top 100 in total defense with WV  having the slightly better defense. It’s also a home game for the Mountaineers which gives them a bit bigger advantage.

Pick: West Virginia -3.5

South Carolina (4-2) at Tennessee (3-2), noon ET

Spread: Tennessee -3.5
Over/Under: 47.5

South Carolina’s offense is hobbled after losing Deebo Samuel to injury. Last week’s win over Arkansas, 48-22, is misleading because half of the points scored were defensive touchdowns. This might be a factor against Tennessee’s defense that is great against both the pass and the run. This game might be slow and boring.

Pick: Tennessee -3.5

Florida State (1-3) at Duke (4-2), noon ET

Spread: Florida State -7
Over/Under: 44

For many, Duke was surprising because of its 4-0 start (which included wins by double-digits). However, all of the teams they competed against weren’t really good and Florida State’s defense is more apt to lock down on the Seminoles and keep them to minimal points.

Pick: Florida State -7

No. 17 Michigan (4-1) at Indiana (3-2), noon ET

Spread: Michigan -7.5
Over/Under: 46.5

With Wilton Speight out for the season, Michigan is literally scrambling to get someone at the quarterback position. It’s probably good, however, that they’ve beaten Indiana 21 consecutive times. My money is still on the Wolverines to win but I’m betting Indiana will cover.

Pick: Indiana +7.5

Boston College (2-4) at Louisville (4-2), 12:20 p.m. ET

Spread: Louisville -22
Over/Under: 55.5

Boston College is bleeding yards, and touchdowns, against the rush like an wounded soldier (allowed a combined 405 yards and seven touchdowns). Most of those yards were gained by quarterbacks and now they’re up against Lama Jackson, who is arguable the best dual-threat QB in town. Jackson is probably licking his chops at having at Boston College.

Pick: Louisville -22

No. 10 Auburn (5-1) at LSU (4-2), 3:30 p.m. ET

Spread: Auburn -7
Over/Under: 44.5

Auburn’s Kerryon Johnson should be salivating at the prospect of going up  against LSU’s defense, one that’s allowed over 190 yards in three of its last four games. Do you really believe LSU has the offense to go toe-to-toe with him? I don’t.

Pick: Auburn -7

Purdue (3-2) at No. 7 Wisconsin (5-0), 3:30 p.m. ET

Spread: Wisconsin -16.5
Over/Under: 50

Purdue is finally coming together this year with close losses against Louisville and Michigan and at least two-touchdown wins in their other three games. This isn’t to say they’ll win against Wisconsin, at least, not on their turf but they’ll stay in the game.

Pick: Wisconsin -16.5

Georgia Tech (3-1) at No. 11 Miami, Florida (4-0), 3:30 p.m. ET

Spread: Miami-Florida -6.5
Over/Under: 53

GT is a juggernaut amassing just under 400 yards on the ground per game. However, Miami-Fl is as tough as it comes in defending against the run. This may be the team that finally puts the brakes on the Yellow Jackets, at least, that’s what I’m expecting.

Pick: Miami -6.5

No. 12 Oklahoma (4-1) vs. Texas (3-2) in Dallas, 3:30 p.m. ET

Spread: Oklahoma -7.5
Over/Under: 64.5

Both of these teams have had disappointing, and unsettling, upsets this season. Texas at the hands of Maryland in its season-opener, and Oklahoma last week against Iowa State. The Sooners need to do some major adjustments in their secondary if they don’t want Baker Mayfield to quickly land them in hot water in this game. Though Sam Ehlinger is also a great quarterback, my money is still on the Mayfield’s experience.

Pick: Oklahoma -7.5

Baylor (0-5) at No. 14 Oklahoma State (4-1), 3:30 p.m. ET

Spread: Oklahoma State -26
Over/Under: 68.5

Will Baylor win a game this year? Maybe, but don’t count on it being this one. The Cowboys offense is averaging 46.8 points per game this year and with nobody to stop them in this game, you’ll see the points piling up on the scoreboard.

Pick: Oklahoma State -26

Virginia (4-1) at North Carolina (1-5), 3:30 p.m. ET

Spread: Virginia -4
Over/Under: 49.5

Virginia beat Boise State on their turf on September 22 and they’ve proved to have a solid offense led by Kurt Benkert. It shouldn’t be too hard for the Cavaliers to win this game. Expect Virginia to have a 5-1 record after this game.

Pick: Virginia 31

Vanderbilt (3-3) at Ole Miss (2-3), 3:30 p.m. ET

Spread: Ole Miss -3
Over/Under: 56

Both of these teams are in a tailspin and there are no signs they’ll recover, so it’s pretty hard to pick the winner loser. Vandy, however, is at the end of a brutal schedule that included games against Kansas State, Alabama, Florida, and Georgia. Perhaps, Vanderbilt will get back to winning ways.

Pick: Vanderbilt +3

Northwestern (2-3) at Maryland (3-2), 3:30 p.m. ET

Spread: Northwestern -3
Over/Under: 49.5

Both of these team are struggling on offense, however, the Terrapins showed grit in their games against Texas and Minnesota whereas Northwestern has been lukewarm in all their games. I have to go with the team that gives the better effort.

Pick: Maryland +3

No. 25 Navy (5-0) at Memphis (4-1), 3:45 p.m. ET

Spread: Memphis -3.5
Over/Under: 72

It’s true that this week there aren’t any games between ranked vs unranked teams which might put you off some, but this game should raise some eyebrows. I expect this to be a hard-fought battle with neither team getting too far out ahead before the other catches up. Nevertheless, the Tigers have the home field advantage and that should count some.

Pick: Memphis -3.5

Colorado (3-3) at Oregon State (1-5), 4 p.m. ET

Spread: Colorado-10
Over/Under: 55.5

I’d hate to end this article on a sour note. If you’re not expecting much action from this game, you’d probably be right. But, to watch Oregon State play without head coach Gary Anderson is intriguing. Will the Beavers finally get things going, especially on defense? At least, they should stay in the game.

Pick: Oregon State +10